According to Leber and Krahnstover the appearance of choroidal sarcomas in eyes already phthisical is merely due to chance, their appearance after tracoma not having been sufficiently proven. Phthisis bulbi however is frequently the result of sarcoma, being brought about through irido-cyclitis. The development of the latter is favored by the tumor, since micro-organisms which have been carried there find favorable conditions for development in the dead cells of the tumor and total necrosis of the tumor is brought about. The inflammation then, in consequence of disturbances in secretion, proceeds to phthisis.
A look at the past . . .. Arch Ophthalmol. 2000;118(9):1186. doi:10.1001/archopht.118.9.1186