In the same manner in which epithelial defects of the cornea are recognized by the green coloration which arises when a solution of fluorescin is instilled into the conjunctival sac, it is possible when the epithelia are intact to demonstrate clinically endothelial defects in the depths of the cornea by the color which fluorescin produced. In addition to losses of endothelium it is possible to recognize changes which render the endothelium permeable. This may be proved experimentally.
A look at the past . . .. Arch Ophthalmol. 2000;118(10):1467. doi:10.1001/archopht.118.10.1467