A 29-YEAR-OLD woman with decreased vision in her left eye (20/80 OS) was found to have bilateral subepithelial honeycomb-shaped opacities on a slitlamp examination (Figure 1).Confocal microscopy demonstrated that the subepithelial deposits were located almost exclusively at the Bowman layer (Figure 2). Genetic analysis revealed Thiel-Behnke corneal dystrophy1 (Figure 3), an autosomal dominant corneal dystrophy of the Bowman layer.2 Two family members had similar findings.
Kobayashi A, Sakurai M, Shirao Y, Sugiyama K, Ohta T, Amaya-Ohkura Y. In Vivo Confocal Microscopy and Genotyping of a Family With Thiel-Behnke(Honeycomb) Corneal Dystrophy. Arch Ophthalmol. 2003;121(10):1498-1499. doi:10.1001/archopht.121.10.1498