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Photo Essay
October 2003

In Vivo Confocal Microscopy and Genotyping of a Family With Thiel-Behnke(Honeycomb) Corneal Dystrophy

Arch Ophthalmol. 2003;121(10):1498-1499. doi:10.1001/archopht.121.10.1498

A 29-YEAR-OLD woman with decreased vision in her left eye (20/80 OS) was found to have bilateral subepithelial honeycomb-shaped opacities on a slitlamp examination (Figure 1).Confocal microscopy demonstrated that the subepithelial deposits were located almost exclusively at the Bowman layer (Figure 2). Genetic analysis revealed Thiel-Behnke corneal dystrophy1 (Figure 3), an autosomal dominant corneal dystrophy of the Bowman layer.2 Two family members had similar findings.

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