A unique characteristic of the ocular circulation is that it is availableto direct, noninvasive evaluation, offering a window to study structural andfunctional changes in the human circulation in diseases affecting not onlythe eye (eg, age-related maculopathy) but also elsewhere in the body (eg,hypertension). Since the first description of fundus fluorescein angiographyin the 1960s by Novotny and Alvis,1 therehave been numerous new methods to evaluate the ocular circulation.
Wong TY. Atlas of Ocular Blood Flow: Vascular Anatomy,Pathophysiology, and Metabolism. Arch Ophthalmol. 2004;122(8):1244-1245. doi:10.1001/archopht.122.8.1244-b