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September 2004

Vitreous and Aqueous Penetration of Orally Administered Gatifloxacinin Humans

Arch Ophthalmol. 2004;122(9):1408-1409. doi:10.1001/archopht.122.9.1408

We read with interest the intriguing study by Hariprasad et al.1 Fourth-generation fluoroquinolones, such as gatifloxacin,certainly hold great potential in the treatment and prophylaxis of endophthalmitisand other ophthalmic infections. We applaud the authors for their study confirminggatifloxacin's significant penetration into ocular fluids. However, we takeissue with their discussion of moxifloxacin in the "Comment" section.

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