In this month’s issue, the Subretinal Surgery Trial (SST) investigatorsreport the outcomes of surgical removal of subfoveal choroidal neovascularization(CNV) compared with a control group of patients with the ocular histoplasmosissyndrome (OHS) and with idiopathic CNV.1,2 Thegoal of the SST was to answer the question of whether surgery offered a benefitover the often unfavorable natural history of the disease. Previously publishedstudies showed promise for a surgical approach,3- 5 butthese studies had no concurrent controls without surgery to determine if theoutcomes were better than the natural history and had limited follow-up todetermine if such outcomes were sustained.
Flynn HW, Scott IU. Now That We Have the Results of the Subretinal Surgery Trials, HowDo We Manage the Patient?. Arch Ophthalmol. 2004;122(11):1705-1706. doi:10.1001/archopht.122.11.1705