Clinical Trials
December 2004

A Randomized Trial of the Effects of Rigid Contact Lenses on MyopiaProgression

Author Affiliations

Author Affiliations: The Ohio State UniversityCollege of Optometry, Columbus.




Copyright 2004 American Medical Association. All Rights Reserved.Applicable FARS/DFARS Restrictions Apply to Government Use.2004

Arch Ophthalmol. 2004;122(12):1760-1766. doi:10.1001/archopht.122.12.1760

Objective  To compare the effects of rigid gas-permeable contact lenses (RGPs)and soft contact lenses (SCLs) on myopia progression in children.

Methods  We randomly assigned 116 subjects to wear RGPs or SCLs. Subjects underwentcycloplegic autorefraction, keratometry, and A-scan ultrasonographic axiallength measurements at each annual visit. All analyses were conducted accordingto the original randomization assignment. The primary outcome measure wasthe 3-year change in spherical equivalent cycloplegic autorefraction.

Results  The mean ± SD spherical equivalent cycloplegic refractiveerror progressed –1.56 ± 0.95 diopters (D) for RGPwearers and –2.19 ± 0.89 D for the SCL wearers duringthe 3 years of the study (analysis of covariance [ANCOVA], P<.001). The axial growth of the eyes was not significantly differentbetween treatment groups (ANCOVA, P = .57).The steep corneal meridian of the RGP wearers steepened 0.62 ± 0.60D, and that of the SCL wearers steepened 0.88 ± 0.57 D duringthe 3 years (ANCOVA, P = .01).

Conclusions  The RGP wearers’ myopia progressed less than that of the SCL wearers.The corneal curvature of the SCL wearers steepened more than that of the RGPwearers, but the axial growth was not significantly different between thegroups. Most refractive error treatment effect was limited to the first yearof the trial. The results of the study provide information for eye care practitionersto share with their patients, but they do not indicate that RGPs should beprescribed primarily for myopia control.