We thank Dr Abramson for his comments on our article. Dr Abramson states that we did not report whether any of the eyes had received previous radioactive plaque therapy or cryotherapy, which could affect motility by causing scarring. While none of our 10 patients (12 eyes) had radioactive plaque therapy, all but patient 1 received prior and/or subsequent cryotherapy. However, in a follow-up study, patients treated with cryotherapy but not subtenon carboplatin showed no motility changes (unpublished data). To our knowledge, restriction in eye movements is not recognized as a common complication of cryotherapy.
Mulvihill A, Budning A, Gnanaraj L, Erraguntla V, Vandenhoven C, Heon E, Gallie BL, Chan HSL. Periocular Chemotherapy for Retinoblastoma: Success With Problems?—Reply. Arch Ophthalmol. 2005;123(1):129. doi:10.1001/archopht.123.1.129-a