I read with great interest the recent article by Klein et al1 regarding digital imaging of age-related macular degeneration (ARMD). This was a validation study of a 6.3-megapixel digital fundus camera in dark-adapted pupils and in pharmacologically dilated pupils vs the gold-standard 35-mm fundus camera, and the study looked at macular changes of ARMD. Klein and colleagues concluded with the detection of the different grades of ARMD being adequate with the digital camera, especially when the pupils were pharmacologically dilated. I congratulate the authors on an elegant and ingenious study. By recognizing the importance of the current high-resolution cameras and the advantage of digital photography, this study could represent a turning point in ARMD imaging. It is now recognized that a 6.3-megapixel digital camera captures details of the retina that are still detectable with great clarity even after significant magnification, a quality lost with the traditional 35-mm slide format and digital cameras of lower resolution.
Salti HIS. Detection of Retinal Pigment Epithelial Changes by Nonmydriatic Fundus Cameras. Arch Ophthalmol. 2005;123(11):1615. doi:10.1001/archopht.123.11.1615-a