This paper reviewed the modern ideas on the subject and considered the toxins produced by intestinal decomposition; the relationship to certain diseases of the cornea, sclera, and uvea; the possible relationship to amblyopia and retrobulbar neuritis, acute and chronic.
Reference: De Schweinitz G. Auto-intoxication in relation to the eye. Arch Ophthalmol. 1906:449.
A look at the past . . .. Arch Ophthalmol. 2005;123(12):1675. doi:10.1001/archopht.123.12.1675