We appreciate the interest of Dr Yuen and colleagues in our study of mood disturbance in patients with GO. We agree that the relatively high prevalence of antidepressant use in the patients who completed our survey only serves to confirm our conclusions about the mood disturbance in this population of patients. Considering that antidepressant use was an exclusion criterion for the analysis, our study actually underestimates the extent of these disturbances. This further underscores the importance of recognizing the emotional consequences of GO when managing these patients.
Farid M, Roch-Levecq A, Levi L, Brody B, Granet DB, Kikkawa DO. Graves Ophthalmopathy and Mood Disturbance—Reply. Arch Ophthalmol. 2006;124(3):427. doi:10.1001/archopht.124.3.427