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June 2007

Scleritis and Peripheral Ulcerative Keratitis With Hepatitis C Virus–Related Cryoglobulinemia

Arch Ophthalmol. 2007;125(6):852-853. doi:10.1001/archopht.125.6.852

In patients with peripheral ulcerative keratopathy (PUK), concomitant scleritis is highly correlated with systemic disease (72.3% of patients), typically systemic vasculitis, rheumatoid arthritis–related vasculitis, or systemic lupus erythematosus–related vasculitis.1 We describe a patient with necrotizing scleritis and PUK associated with hepatitis C virus (HCV)–related cryoglobulinemia. To our knowledge, this is the first description of this association.

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