In the article titled “Analysis of the Macula With Optical Coherence Tomography After Successful Surgery for Proliferative Vitreoretinopathy,” Benson et al1 discussed factors responsible for poor visual acuity following anatomically successful surgery for recurrent retinal detachment.
The study methods raised a few questions in our minds. The investigators proposed to study the morphological changes in the retina that account for visual loss following surgery. Experimental and histopathological studies have shown irreversible photoreceptor loss (apoptosis),2 photoreceptor misalignment, neural retinal remodeling, and subretinal pathological abnormalities such as retinal pigment epithelium multilayering to be responsible for poor visual acuity. None of these factors can be identified by optical coherence tomography (OCT) that has an axial resolution of 10 μm.
Taneja N, Mathai A. Optical Coherence Tomography in Patients With Decreased Visual Acuity After Successful Surgery for Proliferative Vitreoretinopathy. Arch Ophthalmol. 2007;125(6):855. doi:10.1001/archopht.125.6.855-a