The local clinical use of a 30 per cent solution of sodium sulfacetimide was first reported by Dickson. Under the auspices of the Ross Foundation for the Prevention of Blindness, in a trial period of six months, of 11,953 cases of ocular injuries, there were only 7 instances of corneal ulcer, while before the use of this drug 350 cases of corneal ulcer occurred in a three year period. Thus the preventive value is obvious.
Reference: Mayer LL. Sodium sulfacetimide in ophthalmology. Arch Ophthalmol. 1948;39(2):232-235.
A look at the past. . .. Arch Ophthalmol. 2007;125(7):994. doi:10.1001/archopht.125.7.994-a