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July 2007

Perioperative Management of Anticoagulated Patients Undergoing Repeated Intravitreal Injections

Arch Ophthalmol. 2007;125(7):994. doi:10.1001/archopht.125.7.994

Dayani and Grand1 performed 57 vitreoretinal surgeries in patients using warfarin sodium and having subtherapeutic (< 1.49 international normalized ratios), borderline (1.50-1.99 international normalized ratios), therapeutic (2.90-2.49 international normalized ratios), or highly therapeutic (> 2.50 international normalized ratios) values. Although postoperative hemorrhages developed in 2 eyes with subtherapeutic values and 2 eyes with therapeutic values, all cleared without treatment. Thus, Dayani and Grand concluded that vitreoretinal surgery is safe while maintaining anticoagulation therapy.

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