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From the Archives of the Archives
December 2007

A look at the past. . .

Author Affiliations

Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007

Arch Ophthalmol. 2007;125(12):1620. doi:10.1001/archopht.125.12.1620

Thirty-two years ago, Mooren described the form of corneal ulcer which he called rodent, and since then about 35 cases have been more or less accurately described. It begins at the margin of the cornea with a narrow grayish-white infiltration, which in a short time becomes an ulcer. It spreads at intervals with intermittent and often severe signs of irritation (ciliary neurosis), which are out of relation to the corneal process. . . . The ulcer spreads about the margin of the cornea and towards the center with a chronic course of months' duration, and in the majority of cases eventually destroys the entire surface of the cornea. It is usually shallow, and perforation is unusual.