Leprosy has a high incidence of ocular complications, including corneal lesions, lagophthalmos, iridocyclitis, and cataract. Involvement of the trigeminal nerve is common and can result in corneal hypoesthesia. Changes in corneal nerves might be the initial ocular manifestation.1
We describe a patient in whom leprosy developed without any apparent ocular complications. In vivo confocal microscopy, however, revealed abnormal corneal nerves. Being a noninvasive imaging technique, confocal microscopy plays a valuable role in visualization of corneal nerves in that condition.
Zhao C, Lu S, Tajouri N, Dosso A, Safran AB. In Vivo Confocal Laser Scanning Microscopy of Corneal Nerves in Leprosy. Arch Ophthalmol. 2008;126(2):282-284. doi:10.1001/archophthalmol.2007.67