The foregoing isotope experiments have indicated that smoking increases the blood volume of the choroid in experimental animals, provided the dose of nicotine is high. Our photographic experiments indicate that smoking constricts the retinal blood vessels in a few humans, changes them not at all in most, and may actually dilate them on rare occasions.
Reference: Bettman JW, Fellows V, Chao P. The effect of cigarette smoking on the intraocular circulation. Arch Ophthalmol 1958;59(4):481-488.
A look at the past . . .. Arch Ophthalmol. 2009;127(3):349. doi:10.1001/archophthalmol.2008.589