Since the late 1980s, there have been several reports of an association between cataract surgery and age-related macular degeneration (AMD).1- 11 Some report a cross-sectional association1,2,8; some, incidence of AMD after surgery9,10; and yet others report progression to more severe AMD.4,5,10 Still, there are some studies that do not find a significant association after controlling for relevant confounders.12,13 What might explain the disparate results? In my estimation, the diversity of findings in no small part begins with differences in study design.
Klein BEK. Is the Risk of Incidence or Progression of Age-Related Macular Degeneration Increased After Cataract Surgery?. Arch Ophthalmol. 2009;127(11):1528-1529. doi:10.1001/archophthalmol.2009.258