Metastatic panophthalmitis is fairly common and generally follows some acute systemic infection, such as puerperal sepsis, cerebrospinal meningitis, pneumonia and measles. In this paper I am not concerned with panophthalmitis from such causes. I am considering only those rare cases of acute purulent endogenous endophthalmitis occurring in the absence of an acute systemic infection.
Selenkowsky and Woizechowsky J found that in rabbits and cats with many bacteria in the circulating blood the organisms invaded the vitreous of normal eyes. When the bacteremia was slight, however, trauma to the eye was necessary to bring about infection.
Oreste - reported a case of metastatic choroiditis the probable cause of which was an unknown lesion in the gastro-intestinal tract or kidneys. Betti3 reported two cases following contusion of the globe, but the original focus was not found. Verhoeff * reported a case of metastatic intra-ocular mycosis. Terrien B reported a case of suppurating iridocyclitis
Asbill DS. ACUTE PURULENT ENDOGENOUS ENDOPHTHALMITISReport of a Case in the Absence of an Acute Systemic Infection. Arch Ophthalmol. 1933;9(5):820–825. doi:10.1001/archopht.1933.00830010843008