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In ophthalmology, the diagnosis and prognosis of a given condition depend largely on color and on slight differences in color. An image in natural color is, therefore, of immensely greater value than a black and white one, for either scientific or educational purposes. Moreover, there are some conditions that cannot possibly be recorded by the ordinary plate and that are excellently pictured by color photography, e. g., dark red blood vessels in the cornea against a black pupil or a dark brown iris and fluorescein-stained defects in the corneal epithelium.
In the problem of obtaining good color photographs of the human eye, three main difficulties arise: 1. Color plates are very slow; therefore the intensity of the light at the moment of exposure must be very high. 2. The eye can be held motionless for only a short time ; therefore the exposure should be as short as
DEKKING HM. COLOR PHOTOGRAPHY OF THE EYE. Arch Ophthalmol. 1934;11(2):225–228. doi:10.1001/archopht.1934.00830090009001