The presence of hyaline bodies, called by the Germans Drusenbildungen, or granular formations, on the optic disk is rare.
Ophthalmoscopically the disk is seen to be swollen, and one may have the impression that the condition is optic neuritis. The swelling may amount to 12 or 14 diopters. The vision is often unimpaired. More careful investigation shows that the swelling is due to masses of small translucent nodules. These are variously distributed ; they may surround the vessels at their exit from the nerve, thus involving only the central parts of the disk ; in other cases they are situated mainly at the edge of the disk, which they obscure. They may cover the entire surface and even invade the surrounding retina for a limited distance, or they may form a ring round the disk. Both eyes are usually affected in unequal degree. The eyes are often otherwise healthy, but in
JENSEN CDF. HYALINE BODIES (DRUSEN). Arch Ophthalmol. 1935;14(2):269–281. doi:10.1001/archopht.1935.00840080095013