During the past eighteen months I have examined approximately 70 patients with tobacco-alcohol amblyopia, and from these I have chosen 55 for a more careful study. The latter were clinical patients at the Massachusetts Eye and Ear Infirmary and most of them I have examined frequently over a period of many months since they were first admitted to the clinic. This type of amblyopia continues to present many puzzling features, and it is almost as important for one to realize its unsolved problems as it is to know the clinical facts on which diagnosis, prognosis and treatment are based. It is especially important, when trying to evaluate the effect of some newly suggested treatment, to know what the normal course of the disease is and what may be expected without any therapy.
This type of amblyopia is seen in from about 0.3 to 0.5 per cent of
CARROLL FD. ANALYSIS OF FIFTY-FIVE CASES OF TOBACCO-ALCOHOL AMBLYOPIA. Arch Ophthalmol. 1935;14(3):421–434. doi:10.1001/archopht.1935.00840090107006