A careful search of the domestic literature and the available foreign sources on the subject of sulfanilamide therapy has failed to reveal any reference to the use of this drug in the treatment of corneal ulcers. There is some reference to its employment for trachoma1 and for gonorrheal ophthalmia.2 Valuable information of a general character is obtainable in recent articles by Whitby3 and by Lockwood and his co-workers.4
Sulfanilamide was first used as a specific agent against a certain strain of Streptococcus haemolyticus, but its range of activity has been rapidly and greatly widened, so that now it is advocated as a curative agent for a large variety of infections. And it seems that the clinician and the laboratory investigator are vying with each other to uncover additional virtues that may be resident in the drug, either in its original form or in its several derivatives.
BAILEY JH, SASKIN E. TREATMENT OF SEVERE CORNEAL ULCER WITH SULFANILAMIDE. Arch Ophthalmol. 1939;22(1):89–96. doi:10.1001/archopht.1939.00860070105007