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Article
January 1941

EXPERIMENTAL STUDIES OF OCULAR TUBERCULOSISVI. THE EFFECT OF SENSITIVITY AND IMMUNITY ON THE EXPERIMENTAL LESIONS OF OCULAR TUBERCULOSIS

Author Affiliations

BALTIMORE
From the Wilmer Ophthalmological Institute of the Johns Hopkins Hospital and University.

Arch Ophthalmol. 1941;25(1):62-74. doi:10.1001/archopht.1941.00870070076007
Abstract

In the study of the relation of ocular sensitivity, ocular activity and cutaneous sensitivity in immune-allergic rabbits,1 it was noted first that both the course of the ocular tuberculosis and the further development of ocular sensitivity after inoculation of the eyes were restrained in comparison with their development in the normal rabbit after similar inoculation. It was further noted that in the early stages of the ocular tuberculosis in immune-allergic rabbits the ocular activity and ocular sensitivity paralleled each other, but that in the later stages of healing and repair there was a definite lag in the subsidence of the ocular sensitivity after apparent healing of the eyes. This brought up the question that factors other than the subsidence of ocular sensitivity might influence the healing of the local process in the eyes. To study further the influence of general immunity, local sensitivity and possibly local immunity on the

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