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August 1941


Arch Ophthalmol. 1941;26(2):288-290. doi:10.1001/archopht.1941.00870140138011

More than thirty years ago Leslie Paton began to publish, in Brain, in the Transactions of the Ophthalmological Society of the United Kingdom, and as monographs, a series of studies on pathologic changes in the optic nerve in relation to intracranial lesions, tumors of the brain and allied conditions. Much of the material came from the pathologic laboratory and from the wards of the National Hospital for Nervous Diseases—Queen Square, as it was known to neurologists—and concerned patients admitted to the service of Sir William Gowers, Mr. Gordon Holmes and others. This interesting and instructive research, based on a wealth of clinical observation as well as on histologic data, dealt with papilledema, atrophy of the optic nerve and neural changes in disseminate sclerosis and in tabes. The papers presented an unusual amount of well digested evidence on the ophthalmoscopic appearance, the pathologic mechanism and the histologic picture of papilledema.

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