ALLERGY of the eye is, of necessity, a subdivision of allergy of the body as a whole. It is also a subdivision of hypersensitivity. Clinically, urticaria, asthma and iritis or any other allergic lesion of the eye are very different; basically, they must have the same pathologic physiology. The clinical symptoms, signs and pathologic manifestations of allergy depend on the structure of the tissue which is the seat of the allergic reaction.
In 1935 Woods1 presented his monograph on the place of allergy and immunity in ophthalmology. This work deals with experimental studies in general ocular immunology; the relationship of allergy to focal infection, vernal conjunctivitis, trachoma, syphilis and tuberculosis; the antigenic properties and reactions of lens protein and uveal pigment, and the use of nonspecific proteins, autoserums, vaccines and specific serums in therapy. Woods's monograph is an excellent introduction to allergy of the eye from the viewpoint of
DUGGAN WF. VASCULAR BASIS OF ALLERGY OF THE EYE AND ITS ADNEXA. Arch Ophthalmol. 1946;36(5):551-611. doi:10.1001/archopht.1946.00890210561004