UNILATERAL syphilitic primary optic nerve atrophy will almost always become bilateral if not treated properly. If, however, therapy is begun while the atrophy of the optic nerve is limited to one side, involvement of the normal eye may be prevented in a high proportion of cases.1
In my anatomic material of 12 cases of syphilitic primary optic nerve atrophy, death had occurred at a time when the atrophy was confined to one optic nerve in 2. The histologic study of the visual pathways in these 2 cases furnished the clue to the ultimate degeneration of the nerve fibers of both optic nerves.
REPORT OF CASES
—Unilateral syphilitic primary atrophy of the optic nerve in a patient with dementia paralytica.A Negro woman aged 65 presented the characteristic symptoms of dementia paralytica without tabetic involvement of the spinal cord. There were syphilitic aortic insufficiency and roentgenographic evidence of
BRUETSCH WL. UNILATERAL SYPHILITIC PRIMARY ATROPHY OF THE OPTIC NERVESAn Anatomic Study of Two Cases. Arch Ophthalmol. 1948;39(1):80-91. doi:10.1001/archopht.1948.00900020083008