OPHTHALMOLOGISTS are far from understanding completely the mechanism of maintenance and regulation of the intraocular pressure. The supreme governing mechanism most probably consists in a combined action of hormonal and neural elements, similar to the pattern which exists with regard to the endocrine system.
Contradictory reports have been made concerning the influence on the intraocular pressure of the hormone of the posterior lobe of the pituitary gland. Franceschetti and Schläppi,1 however, demonstrated that the increase or decrease of tension depends on the quantity of hormone in action. This shows how complicated the mechanism must be. Possibly other known or hitherto unknown substances may be involved.
The influence of the sympathetic and parasympathetic portions of the autonomic nervous system on various functions of the eyes has long been recognized. Hess2 contributed further to knowledge of this action. From the charts recording his extremely interesting, and not yet published, results
STOCKER FW, HOLT LB, CLOWER JW. CLINICAL EXPERIMENTS WITH NEW WAYS OF INFLUENCING INTRAOCULAR TENSIONI. Effect of Rice Diet. Arch Ophthalmol. 1948;40(1):46-55. doi:10.1001/archopht.1948.00900030049005