ETROLENTAL fibroplasia is a condition usually occurring bilatearlly in premature infants and unilaterally in full term infants. It is characterized by a gray pupillary reflex; retrolental vascular membrane; microphthalmos; shallow anterior chamber, with anterior synechias, a feature which predisposes the eye to the development of secondary glaucoma; remains of an anterior pupillary membrane; spheroidal lens, and searching nystagmus. All the babies in the present series have deep-sunken eyes and a discoloration of the lids, such as is noted in adults after prolonged exertion without proper rest.
I shall report 12 cases of retrolental fibroplasia. I have studied the blood groups in 6 of these 12 cases, including those of the mothers and fathers and determined the Rh factor for each baby. Several infants were given roentgen radiation, the total dose ranging from 400 to 1,000 r, in an attempt to devascularize the membrane.
The first reference to this condition that
PAUL TO. BLOOD GROUPS AND EFFECTS OF ROENTGEN IRRADIATION IN RETROLENTAL FIBROPLASIA. Arch Ophthalmol. 1949;41(6):659-666. doi:10.1001/archopht.1949.00900040676001