IT HAS been observed clinically since the early experiences with corneal homotransplants that a successful graft is occasionally followed by a dramatic clearing of the nebulous cornea of the recipient surrounding the graft. This phenomenon has been commented on by von Hippel,1 Sellerbeck,2 Elschnig,3 Kopp,4 Filatov,5 Welter,6 and Imre,7 among others. Imre pointed out that this clearing of the cornea around a transplant is most apt to occur in cases of interstitial keratitis and presented this fact as evidence that the opacity of the cornea in syphilitic interstitial keratitis is due not to scarring but to "colloidal-chemical" changes in the corneal stroma.
Filatov8 suggested the possibility that transplants of cornea outside the pupillary area might influence the clearing of a central opacity in the pupillary area. This report emphasized the use of paracentral penetrating transplants in cases of dense leukoma in order
FINE M. CLEARING EFFECT OF TRANSPLANTED CORNEA ON THE OPACITY OF THE RECIPIENT CORNEA. Arch Ophthalmol. 1950;43(6):1065-1073. doi:10.1001/archopht.1950.00910011082009