In January 1927 at Kansas City, Kan., a 2 year old white boy had his left eye removed because of a glioma of the retina, verified pathologically. There was no extension into the optic nerve. The boy grew up and married, and in February 1948 his wife gave birth to a girl. In August 1948, when the child was 6 months old, the parents noticed that her right eye was larger than her left.
The first ophthalmic examination was at the Manhattan Eye, Ear and Throat Hospital on October 26, at which time the right eye was noted to be rather large, the cornea steamy, the iris discolored, the tension extremely high as determined by palpation, and the globe injected. Examination the same day, with the patient under ether anesthesia and with the left pupil dilated, showed almost complete detachment of the retina of the left eye, with yellowish white
LAVAL J. GLIOMA OF THE RETINA IN FATHER AND CHILD. Arch Ophthalmol. 1950;44(1):140-145. doi:10.1001/archopht.1950.00910020143010