IN RECENT years attention has been focused on the study of the retinal capillaries in systemic vascular disease, since there is little question that the dynamic physiology of the retina is dependent on the integrity of the capillary circulation. In diabetes, for example, capillary microaneurysms have been described by all workers in this subject as the most characteristic retinal capillary lesion in this disease. In explanation of retinal hemorrhages and so-called exudates, such local vascular disturbances as capillary and precapillary stasis and dilatation were suggested by Elwyn1 some years before retinal capillary lesions were observed histologically. Anatomically, Michaelson and Campbell2 in 1940 pointed out that the deep retinal capillary plexus is a more closely knit meshwork than the superficial and that venous stasis occurs mostly in these deeper capillaries, where exudates and hemorrhages are more numerous.
For some years it has been recognized that in the study of
WEXLER D, BRANOWER G. RETINAL CAPILLARY LESIONS IN MALIGNANT HYPERTENSION. Arch Ophthalmol. 1950;44(4):539-548. doi:10.1001/archopht.1950.00910020549006