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Article
November 1950

OCULAR HYPERTENSION INDUCED BY AIR IN THE ANTERIOR CHAMBER

Author Affiliations

PHILADELPHIA
From the Department of Ophthalmology, Hospital of the University of Pennsylvania, the University of Pennsylvania School of Medicine, and the Children's Hospital.

AMA Arch Ophthalmol. 1950;44(5):691-702. doi:10.1001/archopht.1950.00910020703007
Abstract

THE PURPOSE of this paper is to report observations showing that air injected under normal pressure into the anterior chamber of man and certain experimental animals can induce rapid increases in ocular tension, which may reach very high levels. This action indicates that the injection of air into the anterior chamber is not an innocuous procedure which can be carried out indiscriminately. In certain situations its use is probably contraindicated, the injection of saline solution being preferable. The elevation in tension is caused by obstruction to the flow of aqueous from the posterior to the anterior chamber as a result of a valvelike action between the posterior surface of the air bubble and the anterior surface of the iris. Aqueous therefore is retained behind the iris and, being unable to escape from the eye, causes an increase in ocular tension. As aqueous accumulates in the posterior chamber, the root of

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