[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.145.176.252. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
February 1951

EXPERIMENTAL STUDIES ON EARLY LENS CHANGES AFTER ROENTGEN IRRADIATIONI. Morphological and Cytochemical Changes

Author Affiliations

NEW YORK
From the Department of Ophthalmology, Columbia University College of Physicians and Surgeons, and the Institute of Ophthalmology of the Presbyterian Hospital in the City of New York.

AMA Arch Ophthalmol. 1951;45(2):149-164. doi:10.1001/archopht.1951.01700010154003
Abstract

SINCE it was first shown that roentgen ray cataract could be produced experimentally in mature animals (in guinea pigs by Bossuet,1 in 1909, and in rabbits by Aulamo,2 in 1928), the question of the primary site of radiation injury to the lens and the pathogenesis of the lesion have been discussed by many investigators on the basis of experimental and clinical evidence and have been studied systematically by a few. Most investigators have favored the concept of direct radiation damage to the lens (Bossuet,1 Politzer,3 Rohrschneider,4 Peter,5 Grzedzielski,6 Okusawa,7 Leinfelder and Kerr,8 Goldmann and Liechti,9 von Szily,10 Krückmann,11 Poppe12), whereas others, on the basis of the clinical characteristics of the cataract, have preferred the hypothesis of an indirect radiation effect induced by damage to the structures of the ciliary processes, with consequent nutritional disturbance of the lens

First Page Preview View Large
First page PDF preview
First page PDF preview
×