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Article
May 1951

CORTISONE THERAPY IN CASE OF RHEUMATOID NODULES OF THE EYE IN CHRONIC RHEUMATOID ARTHRITIS

Author Affiliations

NEW YORK
From the Research Service, First (Columbia) Division, the Department of Ophthalmology, Goldwater Memorial Hospital, Department of Hospitals, and the Department of Medicine, Columbia University College of Physicians and Surgeons.

AMA Arch Ophthalmol. 1951;45(5):531-538. doi:10.1001/archopht.1951.01700010543005
Abstract

THE VALUE of cortisone in the treatment of various diseases of the eye has been reported by numerous investigators.1 Reports from Merck & Company claim beneficial results in phlyctenular conjunctivitis, keratitis, iritis, iridocyclitis, uveitis and sympathetic ophthalmia.2 Beneficial effects may result when the drug is administered intramuscularly, by instillation of a saline suspension or by subconjunctival injection; and it is expected that the oral route will prove efficacious. The first two modes of therapy were used in the present case.

The commonest ocular affections seen in conjunction with disease of joints (especially rheumatoid arthritis) are keratoconjunctivitis sicca (Sjögren's syndrome), episcleritis, primary uveal disease, scleritis and conjunctivitis.3 Various authors have reported rheumatic granulomas of the sclera, external ocular muscles, orbital tissue and uveal tract.4 Nodular formations of other causes are described.5 Episcleral nodular tuberculosis may grossly resemble rheumatoid granulomas.6 Except for the case described by

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