IN A PREVIOUS report by two of us,1 preliminary information on the use of terramycin in the treatment of trachoma was given, and the high response of trachoma to this antibiotic was described. In the present study, approximately 700 patients with trachoma, in various stages, were treated with this antibiotic, under an assignment planned by one of us (Y. M.)
Five forms of crystalline terramycin hydrochloride2 were utilized in the present study: crystalline terramycin hydrochloride capsules, for oral administration; crystalline terramycin hydrochloride ophthalmic ointment (0.1%); crystalline terramycin hydrochloride ophthalmic solution (0.5%), and a 0.5 and a 1.0% terramycin hydrochloride ointment compounded in a petrolatum base.
Thirty-eight patients with acute trachoma have been treated to date, including those reported on previously. In 11 of these 38 patients the trachoma was of two-to-seven-days' duration. Six of these 11 patients were treated with 0.5% terramycin hydrochloride ointment four to
MITSUI Y, TANAKA C, TOYA H, IWASHIGE Y, YAMASHITA K. TERRAMYCIN IN THE TREATMENT OF TRACHOMA. AMA Arch Ophthalmol. 1951;46(3):235-244. doi:10.1001/archopht.1951.01700020242001