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The case is recorded of a peculiar pigmented tumor of the iris, which, although not the usual malignant melanoma, was locally invasive and could be expected to have destroyed the eye.
—A girl aged 7 years had a history of a small black spot at 6 o'clock on the iris of the right eye, first noticed at the age of 3 months. Originally the lesion was the size of a pinhead and was located midway between the limbus and the pupillary margin. The lesion became progressively larger and although it had doubled in size in the preceding six months, the parents were not alarmed until the right eye became red, two weeks prior to the child's admission. Examination revealed a blonde, blue-eyed child with fair skin and injection of the bulbar conjunctiva of the right eye. There was a black, nodular mass on the iris of the right eye
Winter FC, Maumenee AE. AN UNUSUAL PIGMENTED TUMOR OF THE IRIS. AMA Arch Ophthalmol. 1951;46(4):438-440. doi:10.1001/archopht.1951.01700020449011