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Article
November 1951

UVEITIS, POLIOSIS, AND ALOPECIA IN SIBLINGSA Case Report

Author Affiliations

ROCHESTER, MINN.
Fellow in Ophthalmology, Mayo Foundation, University of Minnesota (Dr. Walter H. Benedict) and Emeritus Member, Section of Ophthalmology, the Mayo Clinic (Dr. William L. Benedict).

AMA Arch Ophthalmol. 1951;46(5):510-512. doi:10.1001/archopht.1951.01700020523007
Abstract

REPORTS on the incidence of the syndrome of uveitis associated with poliosis, alopecia, dysacousia, and vitiligo include only one instance of the disease in two members of the same family. Salus,1 in 1932, reported the occurrence of Harada's disease two months apart in sisters. A report of two additional typical cases is submitted because of their close occurrence in one family.

In this instance a girl, aged 17, first demonstrated signs of uveitis in February, 1944. Two months later, in April, her next older brother, aged 19, showed a similar condition. The courses of the disease in these siblings were similar in all respects. In neither case did deafness or vitiligo appear.

Case 1.  —A girl of Serbian parents, at the age of 17, in the first week of February, 1944, had in both eyes what was first thought to be conjunctivitis. She complained of a foreign body sensation,

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