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July 1952


Author Affiliations

From the Pathology Laboratory of the Manhattan Eye, Ear & Throat Hospital.

AMA Arch Ophthalmol. 1952;48(1):66-74. doi:10.1001/archopht.1952.00920010069010

TUMORS arising in the pigment epithelium layer of the iris are exceedingly rare, according to reports in the literature. I do not refer here to the clumps of pigment epithelium commonly seen at the pupillary margin or to those cases in which a pigment clump can be seen arising from the posterior layer of the iris as an incidental clinical finding. The latter type has been reported by Schmidt,1 Alt,2 Anargyros,3 and Stock.4 Cases similar to the one I am describing in this paper have been reported by Morax,5 by Asbury,6 and, very recently, by Funk.7 I have not been able to find any similar case reports in a thorough search of the literature or in any textbook, including Duke-Elder's8 and Reese's.9 However, Berliner10 stated:

... The term "melanoma" should be reserved for those structures in which a small hyperplasia of

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