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September 1952

LEPTOSPIRAL UVEITISReport of a Bacteriologically Verified Case

Author Affiliations

From the Walter Reed Army Medical Center, Washington, D. C., and the Veterinary Division, Army Medical Service Graduate School, and Walter Reed General Hospital.

AMA Arch Ophthalmol. 1952;48(3):292-297. doi:10.1001/archopht.1952.00920010300003

UVEITIS has been recognized as a sequel of leptospiral infection since the time of Weil.1 In one of the four cases reported in his original publication iridocyclitis was manifested six weeks after clinical onset of the disease. Goebel,2 in 1917, again drew attention to iridocyclitis in Leptospira icterohaemorrhagiae infections.

Since recognition of infection in man with other leptospiral strains, ocular manifestations have been observed as sequelae of canicola fever,3 swineherd's disease,4 mud (swamp) fever,5 Japanese seven-day fever (nanukayami),3b leptospirosis australis B,6 and Palestine bovine leptospirosis.7 The incidence of ocular involve- ment in the leptospiroses has been varyingly reported as from 10 to 44%.8 This variation reflects the intensity of the search for ocular manifestations. Although not reported in the literature available to us, uveitis is undoubtedly associated with the other leptospiroses of man.

Ocular involvement in the leptospiroses may appear as

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