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Article
September 1952

USE OF TYPHOID VACCINE IN CONTINUOUS INTRAVENOUS INFUSION IN TREATMENT OF EYE DISEASES

Author Affiliations

SAN JUAN, PUERTO RICO

AMA Arch Ophthalmol. 1952;48(3):307-312. doi:10.1001/archopht.1952.00920010315005
Abstract

TECHNIQUE AND MATERIALS  ADMINISTRATION of the continuous type of typhoid infusion which is presented here is usually started early in the morning on a fasting stomach. The patient is covered with one blanket to about the level of the shoulders. It is not necessary to have a nurse in constant attendance, as is the case in the methods described by Solomon and Somkin1 and by Curry and Shaw.2 The reason for this is that no dangerous temperature levels will be reached provided the infusion is given at the recommended rate and dilution.Two cubic centimeters of triple typhoid vaccine, containing 1,000,000,000 killed typhoid organisms per cubic centimeter, is introduced into an infusion flask containing 1 liter of sterile isotonic saline solution. The flask is then shaken so as to make a homogeneous suspension of the dead bacteria. With the patient lying in bed, a 22-gauge intravenous needle, connected

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