ALTHOUGH the use of typhoid vaccine intravenously in the form of a fairly rapid injection has long been a controversial procedure, it has been a most widely used therapeutic agent in ophthalmology. The use of typhoid vaccine intravenously in a slow continuous infusion is a much more recent procedure. In addition to a review of the literature pertaining to the mechanism of the therapeutic action of typhoid vaccine, this paper describes a method of giving typhoid vaccine intravenously as an infusion and presents case reports to demonstrate the advantages of this method.
Since typhoid vaccine was first used, several investigators, particularly in the United States, have attempted to work out procedures of administration whereby rapid and maximal benefit could be obtained without endangering the patient. Much of this work has been done outside the field of ophthalmology. Typhoid vaccine has been used intravenously in the treatment of systemic diseases for
BUXEDA R. USE OF TYPHOID VACCINE IN CONTINUOUS INTRAVENOUS INFUSION IN TREATMENT OF EYE DISEASES. AMA Arch Ophthalmol. 1952;48(3):352-361. doi:10.1001/archopht.1952.00920010360014