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February 1953


Author Affiliations

From the Department of Ophthalmology, Post-Graduate Medical School of New York University-Bellevue Medical Center, and the Eye Service, Bellevue Hospital.

AMA Arch Ophthalmol. 1953;49(2):202-211. doi:10.1001/archopht.1953.00920020207010

HYPOPYON keratitis due to infection with the Gram-negative diplobacillus is an uncommon condition. Since the causative organism is of little general interest, bacteriologists have not studied it intensively. Ophthalmologists, on the other hand, find the organism very important but have given it little attention because of the special techniques required in its study. Petit,1 in 1898, on the basis of his clinical and bacteriologic investigation of three cases, divided diplobacillary infections into two groups. Since then, ophthalmologists have considered central hypopyon keratitis to be due to the diplobacillus of Petit and marginal keratitis or conjunctivitis to be due to the Morax-Axenfeld bacillus (Moraxella lacunata). It is the purpose of this paper to demonstrate that this rather arbitrary division is not well founded on either clinical or bacteriologic grounds.

HISTORICAL REVIEW  In July, 1896, Morax2 published the first paper on the Gram-negative diplobacillus. He described it as the causative

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