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March 1953


AMA Arch Ophthalmol. 1953;49(3):303-312. doi:10.1001/archopht.1953.00920020312008

THE INTRAVENOUS use of corticotropin (ACTH) in the treatment of optic neuritis merits serious consideration. It is my purpose in this paper to review the current literature on the subject and to illustrate the use of the drug by reporting my experience in the successful treatment of a patient with intravenous administration of corticotropin. The case presented itself shortly after publication of the recent article by Gordon and associates1 on their experiences with corticotropin and cortisone therapy in acute ocular conditions, in which they stated that "intravenous drip ACTH is the most effective weapon available today," and after Dr. Allan Wood's report at a meeting of the New York Academy of Medicine, Section of Ophthalmology, on the effectiveness of the intravenous use of corticotropin. Current literature on the use of corticotropin in all fields of medicine is voluminous, but relatively few articles are concerned with its intravenous use.2

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