BEDEWING of the corneal epithelium may be observed in a number of pathologic processes. Generally, there are two prerequisites for its development in patients. There must be excessive hydration or fluid pressure in the underlying stroma ; and the epithelial membrane must be intact and have relatively normal permeability characteristics. As a result of these two factors, fluid collects beneath and between the deep cells of the epithelium. This reduces the transparency of the cornea and gives its surface the classic "ground-glass" appearance of bedewing.
Bedewing of the corneal epithelium may occur in normal eyes when the corneal surface is maintained in contact with hypotonic solution, but this requires artificial circumstances, such as the wearing of a contact lens. Treatment of corneal bedewing in diseased eyes is directed primarily at the underlying pathology ; however, there are many occasions, for example, in the management of patients with acute glaucoma, when the ophthalmologist
SWAN KC. A DEHYDRATING JELLY TO CLEAR CORNEAL BEDEWING. AMA Arch Ophthalmol. 1953;50(1):75-77. doi:10.1001/archopht.1953.00920030078011