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Article
August 1953

USE OF SPECIFIC STREPTOCOCCUS VACCINE IN NON-GRANULOMATOUS UVEITIS

Author Affiliations

BALTIMORE
From the Wilmer Ophthalmological Institute of The Johns Hopkins University and Hospital.

AMA Arch Ophthalmol. 1953;50(2):129-146. doi:10.1001/archopht.1953.00920030134001
Abstract

A PRELIMINARY report, in 1950, on the diagnostic and therapeutic use of Streptococcus vaccines in nongranulomatous uveitis was presented at the 16th International Congress of Ophthalmology.1 This report was based on a study of 60 patients with uveitis, 35 of whom had the nongranulomatous and 25 the granulomatous forms. Fourteen of the patients with nongranulomatous uveitis were treated by desensitization with specific bacterial antigens. This preliminary study indicated the value of intracutaneous tests with Streptococcus antigens in the detection of a specific bacterial hypersensitivity, and of intravenous desensitization with the incriminated organisms in the therapy of nongranulomatous uveitis. Since the presentation of this preliminary report, and up to July 15, 1952, similar studies have been made on 148 additional patients with uveitis and specific vaccines prepared for the treatment of 61 of the patients with the nongranulomatous form. It is the purpose of this paper to report the findings

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