[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
September 1953


AMA Arch Ophthalmol. 1953;50(3):299-302. doi:10.1001/archopht.1953.00920030306006

HYDROCORTISONE acetate (Compound F)1 is similar in appearance to cortisone (Cortone) acetate; it is a milky suspension, and the vial must be well shaken before using. It is to be kept at room temperature.

Hydrocortisone, like cortisone, may be given subconjunctivally, or it may be used in the form of eye drops. However, it should not be given by mouth, nor should it be administered intramuscularly. By the two latter routes hydrocortisone has less than half the efficacy of cortisone; given subconjunctivally or in the form of eye drops, hydrocortisone is immeasurably superior to cortisone and, in fact, is efficacious where cortisone and corticotropin (ACTH) are both ineffective.

To make a 0.5% solution for use as eye drops, each cubic centimeter of the hydrocortisone is mixed in 3 cc. of suitable diluent.2 For subconjunctival injections, the hydrocortisone is used, directly from the vial, 0.5 cc. being given every

First Page Preview View Large
First page PDF preview
First page PDF preview