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November 1953


Author Affiliations


AMA Arch Ophthalmol. 1953;50(5):557-571. doi:10.1001/archopht.1953.00920030567002

IN RECENT years considerable knowledge has been added to our understanding of aqueous outflow. Although it had been known for many years that patients with chronic simple glaucoma had a decreased facility (increased resistance) of aqueous outflow,1 it is through the recent efforts of Goldmann2 and Grant3 that these findings have been placed on a more quantitative basis. The facility of outflow is a coefficient representing the outflow in cubic millimeters per minute per millimeter of mercury pressure gradient. It is, therefore, a measure of the ease with which aqueous can leave the eye. Goldmann determined aqueous outflow and facility of outflow in the undisturbed eye by measuring the turnover rate of fluorescein in the anterior chamber (KF),4 the volume of the anterior chamber (VA), and the difference between intraocular pressure (PO) and episcleral venous pressure (PV). Grant has calculated the facility

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