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Article
November 1953

EXPERIMENTAL RADIATION CATARACTIII. Further Experimental Studies on X-Ray and Neutron Irradiation of the Lens

Author Affiliations

BOSTON; LOS ALAMOS, N. MEX.
From the Los Alamos Medical Center, the Los Alamos Scientific Laboratory of the University of California, Los Alamos, N. Mex., and the Howe Laboratory of Ophthalmology, Harvard Medical School (Dr. Cogan and Dr. Donaldson); Los Alamos Medical Center and the Los Alamos Scientific Laboratory of the University of California (Dr. Goff), and Los Alamos Scientific Laboratory of the University of California (Dr. Graves).

AMA Arch Ophthalmol. 1953;50(5):597-602. doi:10.1001/archopht.1953.00920030607006
Abstract

IN PREVIOUS reports of this series1 describing the ocular events in rabbit eyes following exposure to x-rays and neutrons, abnormalities in the lenses were unexpectedly found at the lowest dose levels used (250 r for x-rays and 1.0 X 109 neutrons/cm.2). It is the purpose of this communication to report the effects on the lenses of rabbits of a single exposure to x-rays and to neutrons at lower dose levels and to present a calculation of the energy released in the lens with exposure to comparable cataractogenic doses of x-rays and of neutrons.

At the outset the difficulties inherent in determining a threshold level may be mentioned. Thus, if no opacification of the lens occurs with a given amount of radiation, the objection may legitimately be raised that the observations have not been followed over a sufficiently long period; it is well known that the lower the

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